Permeation through hydrogel

SZ Song, JR Cardinal, SJ Wisniewski, SW Kim. Mechanisms of solute permeation through hydrogel films An irreversible thermodynamic approach. Abstracts of Papers Presented at the 126th National Meeting of the American Pharmaceutical Association, 1979. 

L-C Dong, Q Yan, AS Hoffman. Macromolecular permeation through hydrogels. Proc Int Symp Controlled Release Bioact Mater Amsterdam 18 261-262, 1991. 

SW Kim, JR Cardinal, S Wisniewski, GM Zenter. Solute permeation through hydrogel membranes, hydrophilic vs. hydrophobic solutes. ACS Symp Ser 127 347-359, 1980. 

Recently, we have examined solute permeation through hydrogel membranes in an effort to develop models which describe in detail the transport phenomena with particular emphasis on the role of water in this process. These studies have utilized p-HEMA and its copolymers, and both hydrophobic and hydrophilic solutes (7., i). It was determined that p-HEMA and its copolymers are permeable to both hydrophobic and hydrophilic solutes. 

Zentner, G. M., Cardinal, J. R., and Gregonis, D. E., 1979, Progestin permeation throirgh polymer membranes III Polymerization solvent effect on progesterone permeation through hydrogel membranes, J. Pharm. Sci 68(6) 794-797. 

GM Zentner, JR Cardinal, J Feijen, S-Z Song. Progestin permeation through polymer membranes. IV. Mechanism of steroid permeation and functional group contributions to diffusion through hydrogel films. J Pharm Sci 68 970-975, 1979. 

YH Bae, T Okano, SW Kim. Insulin permeation through thermosensitive hydrogels. J Controlled Release 9 271-279, 1989. 

Substituting equation 4 into the water flux equation(equation 1) yields a correlation between the water flux(F ) and pressure, which is identical with the empirical relationship suggested earlier by Paul ( ), for solvent permeation through swollen hydrogels ... 

Bae YH, Okano T, Kim SW. Insulin permeation through sensitive hydrogels. J. Control. Release 1989 9 271-279. 

Bell, CE., Peppas, N.A., 1996. Modulation of drug permeation through interpolymer com-plexed hydrogels for drug delivery applications. J. Control. Release 39, 201—207. 

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