Perivascular exudation

CMV retinitis, the most commonly recognized CMV disease associated with AIDS, usually is associated with a painless progressive loss of vision. Patients initially may complain of blurry vision, loss of visual acuity, or floaters. CMV retinitis usually begins unilaterally, but bilateral involvement may occur. Untreated, CMV retinitis invariably leads to blindness. The diagnosis of CMV retinitis is made by funduscopic examination and identification of characteristic findings. Lesions characteristic of CMV retinitis include a fluffy white perivascular exudate frequently associated with hemorrhage. Early diagnosis and treatment are crucial to prevent further visual deterioration. 

With the aim of examining serious adverse events and long-term outcomes of intraocular bevacizumab treatment of retinopathy of prematurity, retrospective analysis of retinopathy of prematurity cases recorded in a prospective computer database was undertaken. Adverse reactions included macular hole and retinal breaks causing rhegmatog-enous retinal detachment, progressive vascular attenuation and perivascular exudation and optic atrophy. One systemic reaction, namely, hepatic dysfunction, occurred in one baby after an intracameral injection [102 ]. 

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