Percutaneous transluminal coronary angioplasty complications

Lembo NJ, Black AJ, Roubin GS, et al. Effect of pretreatment with aspirin versus aspirin plus dipyridamole on frequency and type of acute complications of percutaneous transluminal coronary angioplasty. Am J Cardiol 1990 65(7) 422-426. 

Effects of glycoprotein llb/llla receptor antagonists on the incidence of death or nonfatal myocardial infarction following percutaneous transluminal coronary angioplasty. [ Note Data are from several studies thus reported incidence of complications with standard therapy is not the same for each drug.]... 

Cyclic coronary blood flow variations, such as seen in the Folts experimental model (see above), are observed during coronary interventions85 87 and are a sign predicting immediate complications in patients who underwent angiographically successful percutaneous transluminal coronary angioplasty.88... 

GPIIb/IIIa antagonists have to be administered parenterally. They are currently used prophylactically during intracoronary interventions such as percutaneous transluminal revascularization with balloon angioplasty or intracoronary stenting, as well as to treat acute coronary syndromes like unstable angina and acute myocardial infarction. The main complications... 

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