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Peptide ions differentially-labeled

Reacting the peptides in each sample with an individual, mixed-label reagent adds 145 Da to each peptide. Addition of the same mass allows selection of differentially labeled peptides using a single miz in the first analyzer of a QqQ, QTOF, or TOF/TOF MS/MS instrument. Ion traps cannot be used in iTRAQ analyses because of the low masses of the reporter ions... [Pg.186]


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See also in sourсe #XX -- [ Pg.97 ]




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