Penitrem insecticidal activities

A new halogen-containing member of the penitrem family of indole-diterpe-noids, which have insecticidal activity (1397), is thomitrem A (1466) from Penicil-lium crustosum (1398). The novel dichlorinated calmodulin inhibitor, malbrancheamide (1467), was characterized from the fungus Malbranchea auran-tiaca (1399). The microbe Streptomyces rugosporus produces pyrroindomycin B (1468), which is active against both methicillin-resistant Staphylococcus aureus and vancomycin-resistant Enterococci (1400). The Chinese shrub Acacia confusa has yielded the unusual chlorotryptamine alkaloid 1469, which does not appear to be an artifactual dichloromethane adduct (1401). 

Gonzalez MC, Lull C, Moya P, Ayala I, Primo J, Yufera EP (2003) Insecticidal Activity of Penitrems, Including Penitrem G, a New Member of the Family Isolated from Penicillium crustosum. J Agric Food Chem 51 2156... 

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