Penicillium aurantio-virens

L, and M from Diplodia macmspora (Sphaeropsi-dales) Ch. C is also formed by Penicillium aurantio-virens (on spoiled pecan nuts). The Ch. are myco-toxins related to the cytochalasins and are all cytotoxic, some also have antimicrobial (Ch. A) and phytotoxic (Ch. K) activities. They are formed biosynthet-ically from tryptophan and a polyketide chain (nona-ketides). Some C. induce the formation of multinu-clear cells in mammalian cell cultures. 

Kozlovskii AG, Solov eva TF, Sakharovskii VG, Adanin VM (1981) Biosynthesis of "Unusual" Ergot Alkaloids by the Fungus Penicillium aurantio-virens. Dokl Akad Nauk SSSR 260 230... 

C32H36N2O5 19 C. globosum, Penicillium aurantio-virens Sekita et al. (1973) Sekita et al. (1976) Springer et al. (1976)... 

Among the tropolone compounds found in nature are four tropolone-carboxylic acids,obtained from mold cultures.Two ofthese,stipitatonicadd(CXIV,R = COOH) and stipitatic acid (CXIV, R = H) have been obtained from Penicillium stipitatum (Bentley and Thiessen, 1963). Puberulonic add (CXV, R = COOH) and puberulic acid (CXV, R = H) were obtained from P. aurantio-virens, P. puberulum and P.johan-nioli as well as from strains of the P. cyclopium-viridicatum series (sources quoted in this paper). The infrared spectrum of the sodium salt of the anhydride of stipitatonic... 

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