Penicillin and Similar Antibiotics Human Battle with Bacteria

1 Penicillin and Similar Antibiotics Human Battle with Bacteria 

One solution is to restrict the use of antibiotics so that bacteria would not have much chance of becoming resistant, hi other words, use of antibiotics should be 

Cloxacillin (acid- and penicillinase-resistant) Fig. 7.1 Penicillin G and some of its derivatives 

However, there had been a general wishful notion that the resistant bacterial strains, because they are burdened with extra functionality, could not compete with the nom-esistant strains once the drugs were removed, so that nonresistant bacteria 

Some bacteria, yeast, and other pathogens have developed a mechanism to pump out tetracycline and other antibiotics. This is their way of defending against the antibiotics. Some drugs have been developed to block this pump, so that the antibiotics administered will do its work unimpeded. Recently, such a compound, 5 -methoxyhy-drocarpin (5 -MHC), was isolated from barberry plants. When the antibiotics barberine was administered with 5 -MHC, it was found to inactivate the strain of S. aureus that was resistant to antibiotics such as norfloxacin. 

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