Pellizzari synthesis

An important classical synthesis of 1,2,4-triazoles is the Pellizzari reaction in which an acylhydrazide is condensed with an amide (or thioamide) at high temperature. Variations exist in which the amide component is first activated towards nucleophilic attack as a S-alkyl thioamide salt. Employing this type of approach, S-methyl isothioamide... 

The Pellizzari reaction is the chemical reaction of an amide and a hydrazide to form a 1,2,4-triazole. Dapiprazole is an alpha-blocker that is used to reverse mydriasis after eye examination. The synthesis of dapiprazole starts with construction of a hydrazide-type structure and then follows by ring opening of piperidinone and condensation with the acylhydrazide moiety to form the final product. ... 

Paal-Knorr Pyrrole Synthesis Parham Cyclization Passerini Reaction Patemo-Biichi Reaction Pauson-Khand Reaction Payne Rearrangement Pechmann Condensation Pechmann Pyrazole Synthesis Pellizzari Reaction Pelouze Synthesis Periodic Acid Oxidation Perkin Alicyclic Synthesis Perkin Reaction Perkin Rearrangement Perkow Reaction Peterson Reaction... 

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