PEG-phosphatidyl ethanolamine

Micelles formed by self-assembled amphiphilic polymers (such as PEG-phosphatidyl ethanolamine) can also be loaded with amphiphilic PL-based chelates carrying diagnostically important metal ions such as In and Gd [20]. The final preparations are quite stable and serve as fast and efficient agents for scintigraphy or MR imaging. 

Similar experiments with PEG-phosphatidyl ethanolamine mixed micelles with a core-incorporated amphiphilic " In- or Gd-loaded chelating agent PAP demonstrated fast and efficient gamma and MR visualization of different compartments of the lymphatic system. Upon subcutaneous administration, the micelles penetrate the lymphatics and effect visualization (Figure 6). Micelles mostly stay within the lymph fluid rather than accumulate in the nodal macrophages (because of protective effect of surface PEG fragments) and rapidly move via the lymphatic pathway. 

PBLG), and poly(N-hexyl stearate L-aspartamide), and non-biodegradable hydrophobic polymers like poly(propylene oxide) (PPO) and poly(vinyl) derivatives. The hydrophobic segment can be inert or can possess reactive groups for postfunctionalization. A special group of micelles can finally be obtained from lipid conjugates such as PEG-phosphatidyl ethanolamine (PEG-PE). ... 

---