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Pediatric serum drug concentrations differences

Important Differences in Pediatric Serum Drug Concentrations... [Pg.2636]

Adverse reactions to drugs differ in both type and incidence in the pediatric population. Because of immature metabolic pathways, infants and children may have different metabolic patterns than adults. This at least partially explains why neonates require lower theophylline serum concentrations for the treatment of neonatal apnea and why the incidence of hepatotoxi-city following acetaminophen overdose is much lower in young children than in adults [44,45]. Antibiotic adverse effects unique to the pediatric population may... [Pg.669]

Serum concentration monitoring of various drugs administered to pediatric patients may appropriately give information about the drug but not its metabolites. This may be a problem when children metabolize specific drugs differently than adults with resulting differences in metabolite concentrations or the presence of different metabolites. This has been noted when premature infants... [Pg.663]

See other pages where Pediatric serum drug concentrations differences is mentioned: [Pg.45]    [Pg.50]    [Pg.2636]    [Pg.92]    [Pg.2636]    [Pg.663]    [Pg.96]    [Pg.769]   
See also in sourсe #XX -- [ Pg.2636 ]



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