Peak Height and Sample Volume

RiUe I. Changing the injected sample volume is a powerful way to change dispersion. An increase in peak height—and in sensitivity of measurement—is achieved by increasing the volume of the injected sample solution. Conversely, dilution of overly concentrated sample material is best achieved by reducing the injected volumes. 

It has been shown that 51/2 does not depend on the method of injection (valve injection or impulse injection), but it is a function of the geometry and of the volume of the flow channel [20] (cf. Fig. 2.10, 2.11, and 3.15). 

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