Pars intermedia dysfunction

A diagnosis of ECD is usually confirmed by testing the pituitary-adrenal axis. Single or multiple measurements of plasma cortisol are not diagnostic for ECD. In fact, cortisol concentrations vary widely in normal horses and the values from horses with pars intermedia dysfunction are often within the reference range (Dybdal et al 1994). Additionally, cortisol concentrations may be... 

Cyproheptadine is an antihistaminic and antis-erotonergic agent that also has anticholinergic and sedative effects. It is used for its antihistaminic actions in humans. It has been used with limited success in the treatment of pars intermedia dysfunction in horses. 

Dybdal N O, Levy M 1997 Pituitary pars intermedia dysfunction in the horse Part II. Diagnosis and treatment. In Proceedings of the 15th American... 

Schott H C 2002 Pituitary pars intermedia dysfunction equine Cushing s disease. Veterinary Clinics of North America Equine Practice 18 237-270 Schott H C, Coursen C L, Eberhart S W et al 2001... 

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