Paroxetine disposition

Bertelsen, K.M., Venkatakrishnan, K., Von Moltke, L.L., Obach, R.S. and Greenblatt, D.J. (2003) Apparent mechanism-based inhibition of human CYP2D6 in vitro by paroxetine comparison with fluoxetine and quinidine. Drug Metabolism and Disposition The Biolo cal Fate of Chemicals, 31, 289-293. 

Venkatakrishnan, K and Obach, R.S. (2005) In vitro-in vivo extrapolation of CYP2D6 inactivation by paroxetine prediction of nonstationary pharmacokinetics and drug interaction magnitude. Drug Metabolism and Disposition ... 

Segura H Farre M, Pichini S, Peiro AM, Roset PN, Ramirez A, Ortufio J, Pacifici R, Zuccaro P, Segura J, de la Torre R Contribution of cytochrome P450 2D6 to 3,4-methylenedio> meth-amphetamine disposition in humans use of paroxetine as a metabolic inhibited probe. Clin Pharmacokinet (2005) 44, 649-60. 

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