Parenteral tellurium

Acute oral parenteral tellurium intoxication in animals results in restlessness, tremor, diminished reflexes, paralysis, convulsions, somnolence, coma, and death. Hematuria was prompt and occurred in all animals. Exposure of weanling rats to a diet containing elemental tellurium results in a peripheral neuropathy characterized by segmental demyelination and minimal axonal degeneration. It is noteworthy that functional recovery occurred despite... 

Tellurium excretion patterns depend on the chemical forms and mode of administration of the compounds. Parenterally administered tellurium is excreted mainly in the urine rather than the feces, whereas orally ingested tellurium salts are excreted mainly in the feces (Durbin 1960). After oral dosing to rats, 60 -80% of ingested tellurite is rapidly excreted in the feces. The absorbed tellurium is secreted in the bile and enters the intestine. Small amounts of absorbed elemental tellurium and tellurite are exhaled ( 0.1%) presumably as dime-thyltelluride, and produce a characteristic garlic-like breath odor (De Meio 1946). 

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See also in sourсe #XX -- [ ]

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