Hepatic dysfunction parenteral nutrition

In a prospective study of 994 patients who required parenteral nutrition, hepatic dysfunction was identified by a greater than 1.5-fold increase above of the top reference range... 

The level of these potential carcinogens in some broiled or roasted foods, such as broiled sardines, is about 10 ng/g. This amount is much lower than those used in the carcinogenicity assays. The long-term cumulative effect of the carboline intake may be of great concern. In some experimental studies, tryptophan itself appears to promote the formation of tumors.287-289 Also, a tryptophan-riboflavin photoinduced adduct may have a role in the pathogenesis of hepatic dysfunction observed during parenteral nutrition.290... 

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