Parenteral nutrition adult solutions

Peroxide formation has also been observed in multivitamin solutions for parenteral nutrition. Lavoie and co-workers [30] have studied the action of light, air, and composition on the stability of multivitamin formulations, and also total parenteral nutrition (TPN) admixtures containing and not containing vitamins and fatty acids. They analyzed the generation of peroxide in multivitamin solutions and in TPN for adults and neonates. The analysis of multivitamin solutions for enteral use revealed the presence of peroxides at the initial opening of the bottle. The levels were higher in Poly-Vi-Sol (vitamin A, Vitamin D, and vitamin C, vitamin Bb riboflavin, and... 

Laborie, S., Lavoie, J- ., Pineaut, M., and Chessex, P. (2000), Contribution of multivitamins, air and light in the generation of peroxides in adult and neonatal parenteral nutrition solutions, Ann. Pharmacother., 34, 440M45. 

The removal of polyols, sorbitol and xylitol from the blood of newborns does not differ from that of adults (Bassler et al., 1962 Toussaint, 1969). Therefore, these polyols can also be used with amino acid solutions for the parenteral nutrition of premature infants (Griem and Lang, 1962 Lang, 1963 Mehnert, 1966 Prellwitz and Bassler, 1963). 

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