Parahippocampal area

Recently in a PET study, patients with hallucinations activated the left and right thalamus, right putamen, left and right parahippocampal area and right anterior cingulate (Silbersweig et al. 1995)... 

Functional neuroimaging studies suggest that frontal and occipital brain areas are integral to the anxiety response. Patients with panic disorder may have abnormal activation of the parahippocampal region and prefrontal cortex at rest. Panic anxiety is associated with activation of brain stem and basal ganglia regions. GAD patients have an abnormal increase in cortical... 

We do not yet know if the left-right differences in cortical activation (measured in the waking EEG by Davidson) will persist, or be nullified, or even reversed in REM sleep, but we do know that compared to waking, the amygdala and its directly adjacent cortical areas, the parahippocampal and anterior cingulate regions, are selectively activated in REM sleep and, as discussed in the previous section, that this preferential limbic activation is reciprocal to deactivation of both dorsolateral prefrontal cortices. 

Figure 3. Distribution of histamine-immunoreactive nerve fibers in normal human hippocampal structures. F, fimbriae CA1-CA3, cornu ammonis, areas 1-3 GD, gyrus dentatus S, subilucum PHG, parahippocampal gyrus. From Panula et al.42...

While performing a memory task, cannabis abusers showed less neuronal activation than control subjects in the middle temporal gyrus but areas of higher and lower activation within the parahippocampal gyrus, together with differences in hippocampal activation (Block et al., 2002). 

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