Papain homologues

CA C1 C01.079 Papain homologue (Theileria-type) Potential drug target for East coast fever and theileriosis... 

Glycine max (soybean) (Fabaceae) [seed] Soybean cystatin SC (245 aa 27 kDa 1 Cys homologue of 11 kDa phytocystatins plus N- C-terminal extensions) Papain (10-100 nM IC50 for SC SC constructs devoid of N-terminal or C-terminal extension or both extensions) [162]... 

Solatium tuberosum (Solanaceae) [tuber] Potato Cysteine Protease Inhibitors (PCPIs) (20-25 kDa Kunitz PI homologues - for details see Table 12 ) Cysteine proteases (e.g. Papain, Cathepsins B, H L) - for details see Table 12 [185- 188]... 

Homologues of the classical papaya papain that have been tested for peptide S5mthesis are plant-derived enzymes such as bromelain and ficain. Bromelain extracted from pineapple could be applied in Met- and Leu-enkephalin synthesis in a low water system, reaching 97% yield [27]. Ficain isolated from Ficus glabrata latex was tested in di- and tripeptide synthesis in frozen water medium [23] and was used in the synthesis of Lys and Met oligomers starting from the respective ethyl esters [29]. 

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