Palmityl coenzyme

Transfer from an acyl coenzyme A derivative to a nitrogen nucleophile is also quite common. Typical is the N-acetylation of the amino sugars such as glucosamine. The conversion of palmityl coenzyme A to palmit-... 

Inhibition of citrate-synthase by palmityl-coenzyme A, Biochem. biophys. Res,... 

Biosjmthesis of phosphatidic acid from lysophosphatidic acid and palmityl coenzyme A. 

ViGNAis, P. V., and I. Zabin Synthesis and properties of palmityl adenylate palmityl coenzyme A, and palmityl glutathione. Biochim. biophys. Acta (Amst.) 29,263—69 (1958). 

Senior, J. R., and K. Y. Isselbaoher Direct esterification of monoglycerides with palmityl coenzyme A by intestinal epithelial subcellular fractions. J. biol. Chem. 237, 1454 (1962). 

Wieland, O., and Weiss, L., 1963, Inhibition of citrate-synthase by palmityl coenzyme A, Biochem. Biophys. Res. Commun. 13 26. 

Coenzyme A (CoA) derivatives of bile acids were prepared [33,34] by a modification of the mixed anhydride procedure for the synthesis of palmityl CoA. A yield of 70% was calculated from the quantity of cholylhydroxamate formed after treatment of the CoA derivative with hydroxylamine. By modification of this procedure and purification of the products by chromatography on Sephadex LH-20, aqueous solutions of CoA derivatives of cholic, chenodeoxycholic, deoxycholic, and lithocholic acids were pbtained, frozen at - 70°C, and shown to be free from hydrolysis for several months [35]. 

On the basis of preferential affinities for three different peptide binding sites of the pigeon liver fatty acid synthetase, Ghesterton et al. (1968b) have suggested a regulator role for the ratio of concentrations of acetyl-GoA malonyl-GoA. The competitive effects of acetyl-GoA malonyl-GoA, NADHiNAD", phosphorylated compounds (e.g., fructose 1,6-diphosphate), palmityl-GoA, and free coenzyme A (Brady et al., 1956 Robinson et al., 1963) at concentrations which are... 

---