PAH polyanhydride

CAS name poly[oxy(1,6-dioxo-1,6-hexanediyl)] (adipic) poly[oxy(1,10-dioxo-1,10-decanediyl)] (sebacic) poly[oxy(1,9-dioxo-1,9-non-anediyl)] and 2,10-oxecanedione, homopolymer (azelaic)  

CAS number 26913-47-3 (sebacic polyanhydride) 26968-29-6 (adipic polyanhydride) 26968-31-0 and 27306-28-1 (azelaic polyanhydride)  

Person to discover Bucher and Slade Carothers Hill Rosen, Wnek, Linhardt, Langer Jain, J P Chirkara, D Kumar, N, Expert Opin. Drug Dellv., 5, 8, 889-907, 2008 Carothers, W H, US Patent 2,071,250, DuPont, Feb. 16,1937. 

Details first report on synthesis of aromatic polyanhydride (1909) aliphatic polyanhydrides were reported in 1930-1932 in 1983 polyanhydrides were studied for drug delivery  

Monomer(s) structure acids S-(p-carboxyphenoxy) valeric, 8-(p-carboxyphenoxy) ootanoic, 1,3-bis(p-carboxyphenoxy) propane, 1,6-bis(p-oarboxyphenoxy) hexane, 1,6-bis(o-carboxyphenoxy) hexane, adipic, azeiaic, dodecanedicarboxylic, dodecanedioic, fumaric, isophthaiic, p-carboxyphenoxy acetic, pimelic, sebacic, suberic, terephthalic other erucic acid dimer, ricinoleic acid maleate, ricinoleic acid succinate, 12-hydroxystearic acid succinate photopolymerizable monomers, e.g., methacrylated sebacic acid Goepferich, A Tessmar, J, Adv. Dmg Delivery Rev., 54,911-32, 2002 Jain, J P Chirkara, D Kumar, N, Expert Opin. Drug Deliv., 5, 8,889-907,2008. 

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