Packings for SEC of proteins

A variety of packings have been developed for conventional SEC of proteins, and a summary of the more frequently employed commercially available packings Is presented In Table 1, The most common conventional packings consist of spherical particles constructed of dextrans (eg., Sephadex), agarose (eg., Sepharose and Blo-Gel A), or polyacrylamide (eg., Bio-Gel P). 

Packing Type Range Diameter Pressure Stability 

Electro-Nucleonic, Inc., Fairfield, New Jersey Pierce Chemicals Co., Rockville, Maryland 

The problem of compression of dextran and sepharose packings under hydrostatic pressure has been partially alleviated by covalently cross-linking 

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