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P-glycoprotein efflux pump

Hamilton KO, Backstrom G, Yazdanian MA, Audus KL (2001) P-glycoprotein efflux pump expression and activity in Calu-3 cells. J Pharm Sci 90(5) 647-658. [Pg.254]

Sharom FJ. The P-glycoprotein efflux pump how does it transport drugs J Membr Biol 1997 160(3) 161 175. [Pg.414]

Chishty M, Reichel A, Siva J, Abbott NJ, Begley DJ. 2001. Affinity for the P-glycoprotein efflux pump at the blood-brain barrier may explain the lack of CNS side-effects of modern antihistamines. J. Drug Target 93 223-28... [Pg.652]

This section aims to give an overview of current strategies for modeling transporter systems illustrated by three well-characterized transport systems (l)the P-glycoprotein efflux pump, a prototypical ABC-transporter and a product of the multidrug resistance (MDR-1,ABC-B1) gene, which exports metabolites as well as drugs from various cell types ... [Pg.266]

Sikic, B. Hoth, D. Socks, D. Glenn, S. Marcelletti, J. Walsh, M. J. Multani, P. S. Zosuquidar-chemotherapeutic agent combination for the treatment of cancer patients exhibiting activation of the P-glycoprotein efflux pump mechanism, and methods for the determination of P-glycoprotein expression and/or function. PCT Int. Appl. WO 2007008499, 2007 Chem. Abstr. 2007, 146, 135535. [Pg.159]

J. Walsh, M. J. Multani, P. S. Treatment of cancer patients exhibiting activation of the P-glycoprotein efflux pump mechanism. PCX Int. Appl. WO 2007008499,2007. [Pg.161]


See other pages where P-glycoprotein efflux pump is mentioned: [Pg.267]    [Pg.71]    [Pg.393]    [Pg.241]    [Pg.151]    [Pg.180]    [Pg.165]    [Pg.1942]    [Pg.533]    [Pg.703]    [Pg.629]    [Pg.632]    [Pg.505]    [Pg.506]    [Pg.104]    [Pg.119]    [Pg.126]    [Pg.948]    [Pg.265]   
See also in sourсe #XX -- [ Pg.165 ]

See also in sourсe #XX -- [ Pg.2 , Pg.2 , Pg.79 , Pg.252 ]

See also in sourсe #XX -- [ Pg.79 , Pg.252 ]




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