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P-Glucocerebrosidase

A. General description Alglucerase is a monomeric glycoprotein, with a molecular weight of 59.3 kDa, consisting of 497 amino-acid residues. It is a modified form of P-glucocerebrosidase from pooled human placental tissue. Alglucerase differs from... [Pg.256]

Doering T, Proia RL, Sandhoff K. Accumulation of protein-bound epidermal glucosylceramides in P-glucocerebrosidase deficient type 2 Gaucher mice. FEBS Lett. 1999 447 167-170. [Pg.932]

Castanospermine a-glucosidases (including amyloglucosidase, sucrase. maltase, isomaltase, trehalase, amylase, Glucosidase I and II) and p-glucosidases (including lactase and cellobiase), P-glucocerebrosidase and p-xylosidase ... [Pg.183]

S. Takasaki, G. J. Murray, F. S. Furbish, R. O. Brady, J. A. Barranger, and A. Kobata. Structure of the N-asparagine-like oligosaccharide units of human placental p-glucocerebrosidase. J. Biol. Chem. 259 10112 (1984). [Pg.280]

Sphingomyelinase Ceramidase P-Glucocerebrosidase P-Galactosyl hydrolase P-Hexosaminidase A P-Galactosidase a-Galactosidase P-Hexosaminidases A and B Galactocerebrosidase Arylsulfatase A... [Pg.258]

Gaucher s disease P-glucocerebrosIdase deficiency causes glucocerebrosides to accumulate... [Pg.81]

Jin K, Higaki Y, Tagaki Y, Higuchi K, Yada Y, Kawashima M, Imokawa G (1994) Analysis of P-glucocerebrosidase and ceramidase activities in atopic and aged dry skin. Acta Derm Venereol (Stockh) 74 337-340... [Pg.74]

C. E. Bobst et al. Impact of oxidation on protein therapeutics conformational dynamics of intact and oxidized acid-p-glucocerebrosidase at near-physiological pH. 2010. Protein Sci. 19(12), p. 2366. DOI 10.1002/pro.517. [Pg.295]

Holleran WM, Ginns El, Menon GK, et ah Consequences of P-glucocerebrosidase deficiency in epidermis Ultrastructure and permeability barrier alterations in Gaucher disease. J. Clin. Invest. 1994 93 1756-1764. [Pg.1875]

Withers et al. have reported the development of a new class of fluorosugar glycosidase inactivators (32) bearing tunable phosphorus-based leaving groups that reacted with lysosomal p glucocerebrosidase over 4000 times faster than 2-deoxy-2-fluoro-p-Z)-glucosyl fluoride. ... [Pg.90]

See other pages where P-Glucocerebrosidase is mentioned: [Pg.311]    [Pg.209]    [Pg.284]    [Pg.285]    [Pg.256]    [Pg.257]    [Pg.311]    [Pg.526]    [Pg.130]    [Pg.192]    [Pg.261]    [Pg.452]    [Pg.452]    [Pg.509]    [Pg.311]    [Pg.725]    [Pg.144]    [Pg.81]    [Pg.237]    [Pg.451]    [Pg.451]    [Pg.454]    [Pg.177]   
See also in sourсe #XX -- [ Pg.182 , Pg.192 ]

See also in sourсe #XX -- [ Pg.452 ]

See also in sourсe #XX -- [ Pg.81 ]



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Glucocerebrosidase

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