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Oxygen hypoxia response element

List of Abbreviations HIF, hypoxia-inducible factor HREs, hypoxia response elements Hsps, heat-shock proteins iNOS, inducible nitric oxide synthase NE, noradrenabne ODG, oxygen-dependent genes ROS, reactive oxygen species TH, tyrosine hydroxylase... [Pg.272]

FIGURE 10.2. Hypoxia inducible factor-1 (HIF-1) signaling model. Under normal oxygen conditions (normoxia), HIF- la is hydroxylated and ubiquitinated by HIF-1a inihibitor and is targeted for proteasomal degradation. Under low oxygen conditions (hypoxia), HIF-1a and HIF-113 complex bind to hypoxia responsive element (HRE) in response to the... [Pg.228]


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Hypoxia response

Oxygen element

Oxygen elemental

Oxygen hypoxia

Response elements

Responsive element

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