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Oxygen enzymatic removal

The presence of ascorbate peroxidase (32) in addition to a dehydroascorbate reductase in T. cruzi (91) has led to the suggestion of the occurrence of an enzymatic vitamin C redox cycle that would replenish ascorbic acid for reactive oxygen species removal (91). [Pg.156]

The structure of alpha-0 is designed to overcome these two restrictions. A methyl group on the oxygen (the O-methyl) removes the polarity restriction. A methyl group next to the amine function (the alpha-methyl) protects the molecule from enzymatic attack. With the two obstacles removed, this compound apparently has easy access directly to the brain. Hence, alpha,O-dimethylserotonin (a,0-DMS) goes directly into the central nervous system and has proved to be one of the most potent tryptamines yet described. And it is active following oral administration, where it is exposed to all of the body s protective machinery. [Pg.51]

See other pages where Oxygen enzymatic removal is mentioned: [Pg.365]    [Pg.118]    [Pg.344]    [Pg.69]    [Pg.352]    [Pg.916]    [Pg.5]    [Pg.28]    [Pg.289]    [Pg.30]    [Pg.373]    [Pg.156]    [Pg.34]    [Pg.91]    [Pg.171]    [Pg.40]    [Pg.292]    [Pg.585]    [Pg.222]    [Pg.53]    [Pg.743]    [Pg.19]    [Pg.373]    [Pg.80]    [Pg.156]    [Pg.67]    [Pg.60]    [Pg.40]    [Pg.83]    [Pg.219]    [Pg.272]    [Pg.16]    [Pg.1103]    [Pg.249]    [Pg.298]    [Pg.577]    [Pg.433]    [Pg.212]    [Pg.280]    [Pg.234]    [Pg.1686]    [Pg.402]    [Pg.114]    [Pg.71]    [Pg.223]    [Pg.3]   
See also in sourсe #XX -- [ Pg.149 ]



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