2-Oxopyridine-3-carboxylic acid

Bossio R, Marcos CF, Marcaccini S, Pepino R (1997) Studies on isocyanides and related compounds. A novel synthetic route to 1, 6-dihydro-6-oxopyridine-2-carboxylic acid derivatives. Heterocycles 45 1589-1592... 

Natural product-related l,6-dihydro-6-oxopyridine-2-carboxylic acid derivatives originate from the reaction of aldehyde, amines, phenylglyoxylic acid and isocyanides [133]. 

Other. The pyridine- and A-oxopyridine-2-carboxylates, Am02L2, have been obtained from aqueous solutions of americium(VI) and the acid HL the A-oxide 2-carboxylate is formed as the dihydrate.di-(2-ethylhexylphosphoric acid (HDEHP) solutions have been used to selectively extract Am from Cm in such systems rapid reduction of Am to lower oxidation states is a problem. 

M 02(NC5H4-2-C02)2 HM 02(NC5H4-2-C02)3 M U02(NCsH4-2-C02)3 Pyridine- i-carboxylate.i M 02(NC5H4-3-C02)2 H20 N-Oxopyridine-2-carboxylates M 02iONCsH -2-C02)rxHjO Pyridine-2,6-dicarboxylates (acid = C-jH NO ) [U02(C2H3N04)] ... 

Pyridonecarboxylic acid esters. F2 (diluted with N2) bubbled into a soln. of dimethyl pyridine-2,3-dicarboxylate in 2 1 acetonitrile/water for 20 min at 0 , flushed with N2 for 30 min at room temp., and refluxed for 2 h-+ dimethyl 1,6-dihydro-6-oxopyridine-2,3-dicarboxylate. Y 56%. F.e. inch oxidation of 2-, 3- and 4-carboxypyridines, and of methyl quinoline-4-carboxylate, s. M. Van Der Puy et al.. Tetrahedron Letters 29, 4389-92 (1988). 

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