4-cyclohexyl-4-oxo

Uber eine Metallierung kann man in die Methyl-Gruppe 5-substituicrtcr 2-Methyl-1,3,4-oxa-diazole einen 2-Oxo-propyl- oder 2-Oxo-cyclohexyl-Rest einfiihren659... 

Bicyck>[5.1.0 octan 8-Methoxycarbo-nyl- E19b, 1041 (Carben + En) Butanal 3-(2-Oxo-cyclohexyl)-VII/2b, 1533... 

Methyl-cyclohexyl)-3-oxo- E 19a, 764 (C — B-Spaltung/+ En-on) 1-Buten 4-Cyclohexyl-4-hydroxy-3-methyl- E2lb, 1425/1428/1441/... 

Bis-(2-oxo-cyclohexyl]- VII/2b, 1529 (4-tert.-Butyl-phenyl)-dimethoxy-E3, 247 (CH2C1 -fCHO) E14a/1, 492f./496 [CH3 -CH(OR)2]... 

Methyl-phenylimino)-1 -pyridyl-(2)- 1369 2-(2-Oxo-cyclohexyl)-cyclohexyliden- 208 1 -Oxo-2-cyclopenten-(2)-yl-l -phen yl- 800... 

Combining the rate coefficient values reported above and a diurnal average [OH] = 10 molecule cm provides an estimate of the atmospheric lifetime of carbonyl nitrates with respect to removal by reaction with OH in the range 3 to 30 days. Photolysis is also likely to be an important atmospheric loss mechanism. Wangberg et al. (1996) conclude that the photodecomposition in the troposphere is unimportant for tra 5 -2-hydroxy-cyclopentyl-1-nitrate (no significant absorption) but both 2-oxo-cyclohexyl-l-nitrate... 

Signicant new information related to the photodecomposition of some bifiinctional alkyl nitrates has been reported. In addition to absorption spectra of many alkyl nitrates, Roberts and Fajer (1989) also measured the spectra for the bifiinctional 2-nitrooxyethanol. Bames et al. (1993) studied the absorption spectra and photolysis products of several dinitrates 1,2-propandiol dinitrate, 1,2-butandiol dinitrate, 2,3-butandiol dinitrate, l,4-dinitrooxy-2-butene, 3,4-dinitrooxy-l-butene, as well as several bifiinctional nitrates a-nitrooxyacetone, l-nitrooxy-2-butanone, and 3-nitrooxy-2-butanone. Wangberg et al. (1996) reported on the the atmospheric chemistry of the bifiinctional cycloalkyl nitrates 2-hydroxy-cyclopentyl-l-nitrate, 2-oxo-cyclohexyl-1-nitrate, and frans -l-methyl-cycto-l,2-dinitrate. In this section, we will review the findings related to the tropospheric photodecomposition of these multifunctional nitrates. 

D/chloro-5-Cyclohexyl-2-Oxo-2,3-D/hydro 1 H-Benzo(fj-Diazepine-1,4 fa) Process Using Sodium Hypochlorite — 40 ml of a solution of sodium hypochlorite of 14.5 British chloro-metric degrees are added to a suspension of 5.4 grams of 7 chloro-5 cyclohexyl-2 oxo-2,3-dihydro 1 H-benzo(f)diazepine-1,4 in BO ml of methylene chloride. The mixture is stirred at room temperature for 15 minutes the solid dissolves rapidly. The organic iayer is decanted, washed with water, dried over anhydrous Sodium sulfate and the solvent evaporated under reduced pressure without exceeding a temperature of 30 C. The residue is taken up in a little diisopropyl ether and the crystals which form are dried. They are recrystallized as rapidly as possible from ethyl acetate. Colorless crystals are obtained (3.9 grams yield, B5%) MP < = 163°C, with decomposition. 

Benzenediamine (218) and the hydrochloride of ethyl 2-[A-cyclohexyl-(ethoxyformimidoyl)]glyoxalate [Et02CCOC(OEt)=N(CeHn)] (prepared in situ) gave A-cyclohexyl-3-oxo-3,4-dihydro-2-quinoxalinecarboxamide (222) (PhH-EtOH-CH2Cl, 40°C, 2 h 81% clearly needing an hydrolytic step). o-Anilinoaniline gave ethyl 3-oxo-4-phenyl-3,4-dihydro-2-quinoxalinecarboxy-... 

A fluorinated 2-oxo derivative of 3,4-dihydro-2//-1,3-oxazine (58) was obtained, along with a 2,3-dihydro derivative (59) and an azetidinone, from perfluoromethacryloyl fluoride and cyclohexyl isocyanate190 [Eq. (44)]. 

The reaction of /V-cyclohexyl-/V-(2-pyridyl)carbodiimide and the allenic acid 83 in dry tetrahydrofuran at ambient temperature for 3 days afforded a 2 1 mixture of isomeric 2-oxo-2H- and 4-oxo-4/7-pyrido[l,2-a]pyrimid-ines 88 and 87 instead of the expected Diels-Alder adduct (92HCA1262). The formation of an activated ester 84 was suggested in the first step, which underwent a 1,5- or 1,3-acyl migration, giving rise to the isomeric pyrido(l,2-a]pyrimidines 87 and 88 via acylureas 85 and 86, respectively (Scheme 6). 

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