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Oxidative stress angiogenesis

Gerald D, Berra E, Frapart YM, Chan DA, Giaccia AJ, Mansuy 110. D, Pouyssegur J, Yaniv M, Mechta-Grigoriou F. JunD reduces tumor angiogenesis by protecting cells from oxidative stress. Cell 2004 118 781-794. [Pg.736]

The exact mechanism of anticancer effects of CLA is not clear, and several possible mechanisms could underlie the anticancer properties of CLA. These actions may include its ability to interfere with the proliferation of cancer cells, increased apoptotic cell death, inhibition of angiogenesis, or increased oxidative stress. In a study comparing the effects of CLA on estrogen receptor positive human breast cancer cells (MCF-7) and estrogen receptor negative (MDA-MB 231) cells, CLA was shown to selectively inhibit proliferation of estrogen receptor positive cells. [Pg.1369]

West, X. Z. et al. Oxidative stress induces angiogenesis by activating TLR2 with novel... [Pg.229]

Shono, T., Ono, M., Izumi, H., Jimi, S.-I., Matsushima, K., Okamoto, T., Kohno, K., and Kuwano, M. (1996) Involvement of the transcription factorNF-kappaB in tubular morphogenesis of human mircovascular endothelial cells by oxidative stress. Mol. CeU. Biol. 16,4231—4239. Cao, Y., Chen, C., Weatherbee, J. A., Tsang, M., and Folkman, J. (1995) Gro-beta, a CXC Chemokine, is an angiogenesis inhibitor that suppresses the growth of Lewis lung carcinoma in mice. J. Exp. Med. 182, 2069-2077. [Pg.212]


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See also in sourсe #XX -- [ Pg.384 ]




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Oxidative/oxidant stress

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