Oxidative amination of alcohols

When aromatic amines are allowed to react with allylic alcohols [57], 1,2- [58], and 1,3-diols [59], the corresponding indole and quinoline derivatives are formed (Eqs. 3.20 and 3.21). 

The present principle of the dehydrogenation of alcohols can be applied to catalytic transformations of aldehydes. Esters can be obtained from the reactions of aldehydes with alcohols using RuH2(PPh3)4 as catalyst (Eq. 3.26) [8]. 

A Cannizzaro-type reaction occurs upon treatment of aldehydes with water to give the corresponding esters (Eq. 3.27) [8] or carboxylic acids and alcohols (Eq. 3.28) [64]. In contrast, a similar reaction in the presence of a hydrogen acceptor such as benzylideneacetone affords carboxylic acid selectively (Eq. 3.29) [8]. 

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