Oxidation reactions organophosphorus insecticides

The organophosphorus insecticides are all structurally related and undergo similar reactions. The chemical classification of the most widely used compounds of this type is given in Table V. These compounds can also be differentiated on the basis of whether they are largely effective per se or undergo oxidative conversions in plants or animals. All are inhibitors of the enzyme, cholinesterase. Their potency depends not only upon their intrinsic enzyme affinity but also on anticholinesterase properties acquired through in vivo metabolism. 

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