Oxalohydroxamic acid

Hydroxamic acids of general structure R—CO—NH—OH, having R as an organic residue, have been known since 1869 with the discovery of oxalohydroxamic acid by Lossen . Despite this, researches on these compounds were lacking until the 1980s, after which an enormous amount of information has accumulated with respect to their biomedical applications, synthesis, and the determination of the structures of their metal complexes. ... 

The name hydroxamic acid was first used by Lossen6 in 1869, in the case of oxalohydroxamic acid, obtained from diethyl oxalate and hydroxylamine. Where this grouping forms part of the main cyclic system, however, the compound is named as a derivative of this system. In this review, 2 and 3 would be named as l-hydroxy-2-pyrrolidone and l-hydroxy-2-pyridone, respectively. 

OXALOHYDROXAMIC ACID AS A REDUCTOMETRIC TITRANT FOR THE DETERMINATION OF OXYGEN TO METAL RATIO IN NUCLEAR FUEL... 

Oxalohydroxamic Acid as a Reductometric Titrant Scheme for stoichiometric reaction of Ce (fV) and OH A ... 

Oxalohydroxamic acid is a strong reducing agent. It has been used as a primary standard. Stoichiometry of the redox reaction i.e. OHA and Cerium (IV) is established earlier. The course of reaction is described by the scheme and end product analyses. These facts are implemented simply and successfully for the determination of 0/M in nuclear fuel. Analysis of U3O8 sample is precisely reported in the proposed method. 

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