Ovomucid

The presented algorithm was applied to 4 proteins (lysozyme, ribonuclease A, ovomucid and bovine pancreatic trypsin inhibitor) containing 51 titratable residues with experimentally known pKaS [32, 33]. Fig. 2 shows the correlation between the experimental and calculated pKaS. The linear correlation coefficient is r = 0.952 the slope of the line is A = 1.028 and the intercept is B = -0.104. This shows that the overall agreement between the experimental and predicted pKaS is good. 

Figure 7 Correlation between predicted and experimental pK s in nine globular proteins hen egg white lysozyme, ribonuclease A, turkey ovomucid third domain, bovine pancreatic trypsin inhibitor, B1 and B2 immuno obulin G binding domains of protein G, a-chymotrypsin, ribonuclease Tj, lysozyme T4, and staphylococcal nuclease.

W. Schaller and A. D. Robertson, Biochemistry, 34, 4714 (1995). pH, Ionic Strength and Temperature Dependences of Ionization Equilibria for the Carboxyl Groups in Turkey Ovomucid Third Domain. 

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