Overload proteinuria

Eddy, A.A. Glachelll, C.M. Renal expression of genes that promote Interstitial Inflammation and fibrosis In rats with protein-overload proteinuria. Kidney Int 1995 47 1546-1557. 

Thus, proteinuria may be due to an alteration in the structural integrity of the glomerular nitration barrier, injury to the tubular cells, saturation of the reabsorp-tive mechanisms of the tubular cells, injury to other parts of the renal tract, protein overload from the plasma (e.g., myoglobinuria in acute renal failure following rhab-domyolysis), or renal hemodynamic effects at the glomeruli (Bernard and Lauwerys 1991 Schurek 1994). The broad patterns of proteinuria may be summarized as... 

The acute nephritic syndrome includes haematuria, proteinuria, oliguria, and volume overload (Cameron 1979). Elevated serum creatinine levels are another common finding. This presentation is typical for acute postinfectious glomerulonephritis (GN) and rapidly progressive GN. Other forms of GN, such as membranoproliferative GN, lupus nephritis, and shunt nephritis may also manifest as an acute nephritic syndrome. 

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