Outer plexiform layer

Figure 14.1 Schematic diagram of the blood-retinal barrier (BRB). The retinal cell layers seen histologically consist of retinal pigment epithelium (RPE) photoreceptor outer segments (POS) outer limiting membrane (OLM) outer nuclear layer (ONL) outer plexiform layer (OPL) inner nuclear layer (INL) inner plexiform layer (IPL) ganglion cell layer (GCL) nerve fiber layer (NFL) inner limiting membrane (ILM).

Inner nuclear layer Outer plexiform layer Henle fiber layer Photoreceptor outer nuclear layer Photoreceptor inner segment layer... 

Inner nuclear layer Outer plexiform layer... 

Messersmith EK, Redburn DA. 1990. Kainic acid lesioning alters development of the outer plexiform layer in neonatal rabbit retina. Int J Dev Neurosci 8 447-461. 

In the rat retina, mGluR5 immunoreactivity in the outer and inner plexiform layers was further observed electron-microscopically immunoreactivity in the outer plexiform layer was in dendrites of rod bipolar cells postsynaptic to rod photoreceptor terminals, while that in the inner plexiform layer was seen in amacrine cell processes postsynaptic to OFF-cone bipolar cell terminals, ON-cone bipolar cell terminals, and rod bipolar cell terminals (Koulen et al., 1997). 

Species Outer segments layer Inner segments layer Outer nuclear layer Outer plexiform layer Inner nuclear layer Inner plexiform layer Ganglion cell layer Miiller cells... 

Figure 6 A series of spectra (right) from the various layers of a pigmented rat retina (left). Spectra were collected from photoreceptor outer segments (OS, spectrum 1), inner segments (IS, spectrum 2), outer nuclear layer (ONL, spectrum 3), outer plexiform layer (OPL, spectrum 4), inner nuclear layer (INL, spectrum 5), and inner plexiform layer (IPL, spectrum 6). Note the elevated absorbance values for 0= C-H (B), CH2 (C) NH (A), 0=0 (D) in the outer segments and the elevated absorbance values for P = 0 (E) and H-C-OH (F) in the outer nuclear layer. The CH2 NH ratio is also large in the inner plexiform layer. (Reprinted with permission from LeVine SM, Radel JD, Sweat JA, and Wetzel DL (1999) Microchemical analysis of retina layers in pigmented and albino rats by Fourier transform infrared microspectroscopy. Biochimica et Biophysica Acta-General Subjects 1473 409-417 Elsevier.)...

Fig. 4-36. Survey picture of cross section through the rabbit retina. From top to bottom choroid layer and pigment epithelium (PE) layer of the outer segments (OS) of the receptor cells the inner segments (IS) outer nuclear layer (ON) outer plexiform layer (OP) inner nuclear layer (IN) inner plexiform layer (IP) and ganglion cell layer (GL), represented by a single ganglion cell embedded in the foot processes of the Muller cells, the equivalent of the glial cells in the central nervous system. Note the extensive convergence in the retinal circuity in this part of rabbit retina, reflected in the successive reduction of conducting elements in the direction of receptor cells to ganglion cells, x 1,700. (From Sjostrand)...

Fig. 3. Confocal immunofluorescence showing RP2 localization in photoreceptors of the human retina. An 80-pm Vibratome section of human retina stained with rabbit hRP2-337-350 antiserum was detected with Cy3 conjugated donkey anti-rabbit and visualized by optical sectioning using a Zeiss LSM510 confocal microscope. OPL outer plexiform layer ONL outer nuclear layer OLM outer limiting membrane IS inner segment OS outer segment. Scale bar is 10 pm.

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