Outcomes positive versus negative

Figure 44-25 Odds ratios for death and myocardial infarction in short- and long-term followup among cardiac troponin-positive versus cardiac troponin-negative patients with non-ST segment elevation acute coronary syndromes, and for a subset of patients with unstable angina. (From Ottani F, Galvani /M, N/co//n/ FA, Ferrini D, Pozzati A, Di Pasquaie G, et at. Elevated cardiac troponin levels predict the risk of adverse outcome in patients with acute coronary syndromes. Am Heart J 2000 140 917-27.)...

For understanding sensitivity, specificity, false negative predictive value, and false positive predictive value, consider the four cells and two column margins of Table 2, where individuals are cross-classified with respect to their true sero-status versus observed sero-status. Sensitivity is represented by Se = / (testing outcome + truth is +) and specificity is Sp = / (testing outcome - truth is -). With these definitions and with p denoting the probability of an individual having... 

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