Other Methods of Immunosuppression

Immune function can also be suppressed by using antibodies that interact with specific immune system cells and interfere with the cell s function (Table 37-2).13,47 These antibodies can be obtained from animal sources and cell culture techniques (monoclonal antibodies) to provide a rather selective method of suppressing 

Generic Name Trade Name Primary Indication(s) 

Antithymocyte globulin — Treatment of rejection of kidney, heart, liver, lung, pancreas, and bone marrow transplants 

Muromonab-CD3 monoclonal antibody Orthoclone OKT3 Acute rejection of heart, liver, and kidney transplants 

Rh0(D) immune globulin BayRho-D, RhoGAM, others Prevention of Rh hemolytic disease of the newborn 

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