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Osmotic response elements

Figure 6.18. The three common elements in the osmosensory signal transduction cascade of cells (1) osmosensors that monitor osmolality (2) signal transduction pathways that transmit the information provided by the primary osmosensors to (3) osmotic response elements that regulate gene expression and activities of proteins (enzymes and transporters) that are essential for osmotic adaptation. Figure 6.18. The three common elements in the osmosensory signal transduction cascade of cells (1) osmosensors that monitor osmolality (2) signal transduction pathways that transmit the information provided by the primary osmosensors to (3) osmotic response elements that regulate gene expression and activities of proteins (enzymes and transporters) that are essential for osmotic adaptation.
Ferarris, J.D., C.K. Williams, K.-Y. Jung, J.J. Bedford, M.B. Burg, and A. Garcia-Perez (1996). ORE, a eukaryotic minimal essential osmotic response element the aldose reductase gene in hyperosmotic stress. J. Biol. Chem. 271 18318-18321. [Pg.286]

Ko, B.C. et al., 2002, Fyn and p38 signaling are both required for maximal hypertonic activation of the osmotic response element-binding protein/tonicity-responsive enhancer-binding protein (OREBP/TonEBP). J. Biol. Chem. 277(48) 46085-46092. [Pg.260]


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