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Orthoclone OKT

ORTHOCLONE OKT 3 Muronomab-CD3 Ortho Biotech Reversal of acute kidney transplant rejection, reversal of heart and liver transplant rejection... [Pg.694]

Antibodies Avastin, Bexxar, Erbitux, Herceptin, Humaspect, Humira, Mabcampath/Campath-Hl, Mabthera/ Rituxan, Mylotarg, Neutrospec, Oncoscint, Orthoclone OKT-3, Prostascint, Raptiva, Remicade, Simulect, Synagis, Xolair, Zenapax, Zevalin... [Pg.32]

Antibodies have and likely will find additional use in transplantation-related medicine. In general, cell-mediated immunological mechanisms are responsible for mediating rejection of transplanted organs. In many instances, transplant patients must be maintained on immunosuppressive drugs (e.g. some steroids and, often, the fungal metabolite cyclosporine). However, complications may arise if a rejection episode is encountered that proves unresponsive to standard immunosuppressive therapy. Orthoclone OKT-3 was the first monoclonal antibody-based product to find application in this regard. [Pg.395]

Muromonab Orthoclone OKT 3 Prophylaxis of rejection after heart transplantation immunosuppression 1986/1992... [Pg.88]

The first therapeutic antibody approved (Orthoclone OKT-3 or Muromonab CD3, 1986) was indicated not for cancer treatment, but for controlling acute rejection of transplanted organs (kidney, heart, and liver). Nowadays, other clinical indications such as asthma, rheumatoid arthritis, psoriasis, and Crohn s disease are treated with mAbs (see Chapter 17) (Antibody Engineering and Manufacture, 2005 Monoclonal Antibodies and Therapies, 2004 Hot Drugs, 2004 Walsh, 2004). [Pg.6]

Monoclonal antibody against CD3 Orthoclone OKT , Ortho Biotech Prevention of organ rejection... [Pg.4]

See other pages where Orthoclone OKT is mentioned: [Pg.836]    [Pg.434]    [Pg.325]    [Pg.15]    [Pg.405]    [Pg.456]    [Pg.859]    [Pg.395]    [Pg.665]    [Pg.669]    [Pg.325]    [Pg.836]    [Pg.434]    [Pg.325]    [Pg.15]    [Pg.405]    [Pg.456]    [Pg.859]    [Pg.395]    [Pg.665]    [Pg.669]    [Pg.325]    [Pg.721]   
See also in sourсe #XX -- [ Pg.3 , Pg.380 , Pg.395 ]

See also in sourсe #XX -- [ Pg.3 , Pg.34 , Pg.289 , Pg.290 ]

See also in sourсe #XX -- [ Pg.3 , Pg.598 ]

See also in sourсe #XX -- [ Pg.3 ]

See also in sourсe #XX -- [ Pg.3 , Pg.1569 ]

See also in sourсe #XX -- [ Pg.3 , Pg.251 ]

See also in sourсe #XX -- [ Pg.3 ]

See also in sourсe #XX -- [ Pg.3 ]

See also in sourсe #XX -- [ Pg.3 ]



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Muromonab-CD3 (Orthoclone OKT

Orthoclone

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