Orlistat Antidiabetics

Beneficial results in the glycemic profile (mean reduction of fasting glucose by about 0.8 mmol/L) have been reported with orlistat-induced weight loss in 6- to 12-month studies in obese type 2 diabetic patients. This has been found also when orlistat was given as an adjunct to antidiabetic treatment such as with metformin and sulphonylurea drugs. Smaller but significant reductions of HbAlc have also been found by orlistat treatment (placebo controlled). 

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