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Organosilane Reduction of Ketones

Ph2SiH2, (Ph3P)3RuCl2 or (Ph3P)3RhCl (5sl0-4 M) [Pg.345]

The selective organosilane reduction of ketone functions can be effected in the presence of a number of other functional groups including epoxides,320,366 ketals,86,367 thioketals,368 other ketones,369,370 /1-lactams,371 alkynes,372 esters,79,80,83,84,87,320,373,374 a-bromides,76,80,83 amides80,83,84,86,276,320,375... [Pg.74]

The organosilane reduction of ketones in the presence of alcohols provides an excellent route to unsymmetrical ethers. The reaction of cyclohexanone with ethanol and Et3SiH/TFA gives cyclohexyl ethyl ether in good yield.327,328 The... [Pg.80]

Because the organosilane reduction of ketones passes through a positively charged intermediate via the complexation or protonation of the carbonyl oxygen, the presence of suitably placed C=C functions can lead to cyclizations with the hydride of the silane adding to the C=C group. This strategy applies to... [Pg.86]

See other pages where Organosilane Reduction of Ketones is mentioned: [Pg.76]    [Pg.80]    [Pg.110]    [Pg.345]    [Pg.346]    [Pg.348]    [Pg.350]    [Pg.352]    [Pg.354]    [Pg.356]    [Pg.358]    [Pg.360]    [Pg.362]    [Pg.364]    [Pg.366]    [Pg.368]    [Pg.370]    [Pg.372]    [Pg.374]    [Pg.376]    [Pg.378]    [Pg.380]    [Pg.382]    [Pg.384]    [Pg.386]    [Pg.388]    [Pg.390]    [Pg.392]    [Pg.394]    [Pg.396]    [Pg.398]    [Pg.400]    [Pg.402]    [Pg.404]    [Pg.406]    [Pg.408]    [Pg.410]    [Pg.412]    [Pg.414]    [Pg.416]    [Pg.418]    [Pg.420]    [Pg.422]    [Pg.424]    [Pg.426]    [Pg.428]   


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Asymmetric Organosilane Reduction of Ketones

Asymmetric Organosilane Reduction of a,-Unsaturated Ketones

Ketones organosilanes

Organosilane Reduction of a, p-Unsaturated Ketones

Organosilane Reductions

Organosilane Reductive Amination of Aldehydes and Ketones

Organosilanes

Reductive, of ketones

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