Organometallic compounds Organolithium reagents

Before we describe the applications of organometallic reagents to organic synthesis, let us examine their preparation. Organolithium compounds and other Group I organometallic compounds are prepared by the reaction of an alkyl halide with the appropriate metal. 

Organolithium reagents are also valuable in the synthesis of other organometallic compounds via... 

Decarboxylation reactions of metal carboxylates [Eq. (1)], are of increasing value in the synthesis of organometallic compounds (1-5). The reverse reaction, e.g., carbonation of Grignard and organolithium reagents (6,7), is a well-known source of carboxylic acids. Early reviews of the... 

Metathesis reactions continue to be extensively employed in the synthesis of organomercury compounds. While most reactions involve the use of organolithium or Grignard reagents, other organometallic compounds are sometimes used as starting materials. 

Another useful method of preparing organolithium reagents involves metal-metal exchange. The reaction between two organometallic compounds proceeds in the direction... 

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