Organometallic Complexes in Life Science

At a first glance it seems that the special properties of M-C bonds are not involved in biological systems. The well-known coenzyme B12, in which a cobalt- 

In radiopharmaceutical chemistry, the only exception is the Tc(I) isonitrile complex [99mTc(CN-R)6]+ (R is methoxy isobutyl isonitrile) which has found its way to routine clinical application for myocardial imaging [34, 35]. This organometallic complex is probably the most successful radiopharmaceutical 

The preparation of low-valent complexes such as [99mTc(CN-l )6]+ from water might still initiate research in the field of organometallic compounds for fife science. The paradigm that organometallic compounds are not compatible with conditions imposed by biological systems could clearly be repudiated with this compound. 

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