Organometallic Chemistry on Polymeric Supports

The organometallic reagents are very useful in solid-phase organic synthesis, as described in Section 3.3.2. Metal complexes [277] have found application too, as 

Asymmetric organocatalysis in solid-phase chemistry has been recently reviewed [280], 

The multicomponent reactions have been widely used in solid and solution-phase chemistry during the last years. Multicomponent reaction strategies offer significant advantages compared with conventional liner type syntheses. Three or more reactants come together in a one pot reaction to form new products that contain portions of all the components [281]. There are several well-known multicomponent reactions that have been used in combinatorial chemistry. 

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