Organic solvents second-generation effects

The application of enzymatic acylation for the resolution of racemic alcohols in organic solvent has shown to be an effective method to rapidly synthesize chiral alcohols. The racemic alcohols are treated with the lipase and acylating agent one enantiomer remains unconverted whereas the second enantiomer is esterified and easily separated by distillation (Scheme 7.2). Vinyl acetate or isopropenyl acetate are typical acylating agents, as the generated vinyl alcohol tautomerizes rapidly... 

The behaviour of the modified fabrics when wet with the two organic solvents shown in Table 5.2 and Fig. 5.5 and 5.6 (95% ethanol and acetone, respectively) differed from those wet with aqueous media in three fundamental aspects (1) maximum tension took longer to achieve with these solvents than those wet with aqueous media (2) the tension developed was also less than those exposed to aqueous media and (3) the reversal of load and pressure occurred over relatively short time periods due to the high vapour pressure and accompanying evaporation of solvent. Fabrics wet with ethanol took about 450-550 seconds to reach maximum stress (138 psi generated), then reversed this effect due to slow solvent evaporation (Fig. 5.5). Fabrics wet with acetone reach maximum tension more rapidly (150 seconds with a corresponding load of 1.61b and 56 psi), but rapidly reversed back to zero load after 250 seconds due to the complete evaporation of the solvent (Fig. 5.6). 

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