Oral hypoglycemics side effects

Therapeutic use in hypertension The cardioselective p-blockers are useful in hypertensive patients with impaired pulmonary function. Since these drugs have less effect on peripheral vascular p2 receptors, coldness of extremities, a common side effect of p-blocker therapy, is less frequent. Cardioselective p-blockers are useful in diabetic hypertensive patients who are receiving insulin or oral hypoglycemic agents. 

A. One of the most common side effects of oral hypoglycemic agents is gastrointestinal disturbance. 

Drug Interactions Contraceptive effects are decreased when "the pill" is taken with ANTIDIOTICS (ampicillin, isoniazid, neomycin, pen V, rifampin, sulfonamides, tetracycline) or CNS AGENTS (barbiturates, benzodiazepines, phenytoin). Contraceptives increase the effects of corticosteroids and worsen side effects of tricyclic antidepressants. Oral contraceptives decrease the effectiveness of oral anticoagulants, anticonvulsants, and oral hypoglycemic agents. 

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