Optomotor responses

Visual Stereotyped behavioral response to a sudden decrease in illumination Optokinetic / optomotor responses Kimmel et al.218... 

Neurotoxicity [80] Effects on the visual system were tested by the optokinetic and optomotor response assay in 8-dpf zebrafish larvae using 27 drugs including 19 compounds known to cause effects on human vision. Thirteen of the positive compounds provoked effects in zebrafish as well. Two false positives could be attributed to having direct effects on movement not related to disturbance on the visual system. 

The optomotor response assay using 8-dpf zebrafish was used to test 9 different drugs with know effects on human vision. Seven of the tested compounds were positive in zebrafish larvae as well. 

Abdeljalil J, Hamid M, Abdel-Mouttalib O, Stephane R, Raymond R, Johan A, Jose S, Pierre C, Serge P (2005) The optomotor response a robust first-line visual screening method for mice. Vision Research 45 1439-1446. 

Kretschmer F, Kretschmer V, Kunze VP, Kretzberg J (2013) OMR-arena automated measurement and stimulation system to determine mouse visual thresholds based on optomotor responses. PloS One 8 e78058. 

The explanation advanced by Kennedy and Marsh (1974) for the zigzag behavior was that the successive turns were initiated after the loss of the scent the turn carried the moth back towards the direction where the scent was last sensed. (The direction towards the source, however, would be detected by the optomotor response discussed previously.) Gomplementary evidence that such turns are initiated by the loss of the plume come from Traynier s (1968) wind tunnel observations with the moth Anagusta kuhniella in homogeneous pheromone clouds moths were reputed to fly upwind in a straight path (see also the end of this section). 

---