Optimization of Enantiomeric Separations in the New Polar Organic Mode

2 Optimization of Enantiomeric Separations in the New Polar Organic Mode 

2 Method Development and Optimization of Enantiomeric Separations Using. .. 

An example of the effect of acid and base concentration on the separation of propranolol is shown in Fig. 2-13. In this case, the baseline separation is achieved by adjusting the concentration without changing the acid/base ratio. 

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