Optical rotatory dispersion application

C. Djerassi, Optical Rotatory Dispersion Applications to Organic Chemistry (New York, McGraw-Hill, 1960) L. Velluz, M. Legrand, and M. Grosjean, Optical Circular Dichroism, Principles, Measurements, and Applications (Weinheim, Verlag Chemie, 1965) and G. Snatzke (ed.), Optical Rotatory Dispersion and Circular Dichroism in Organic Chemistry (London, Heyden Son, 1967). 

C. Djerassi, Optical Rotatory Dispersion, Applications to Organic Chemistry, McGraw-Hill, New York, 1960. 

Optical Rotatory Dispersion, Application of, and Circular Dichroism to the Study of Biopolymers (Tinoco,Jr.). 18 81... 

Djerassi, C. (ed.) Optical rotatory dispersion Applications to organic chemistry. New York McGraw-Hill 1960. 

Blaha, K., Fri6, 1., and Jakubke, H.-D. (1967). Collect. Czech. Chem. Common. 32, 558-569. Blout, E. R. (1960). In Optical Rotatory Dispersion. Application to Organic Chemistry (C. 

Djerassl, C. "Optical Rotatory Dispersion Applications to Organic Chemistry" McGraw-HllltNew York, 1960 pp. 41-48. 

Djerassi C (1960) Optical Rotatory Dispersion Applications to Organic Chemistry. New York McGraw Hill. Heller W (1972) Optical Rotation - Experimental Techniques and Physical Optics. In Weissherger A and... 

Crabbe, P., Applications of Optical Rotatory Dispersion and Optical Circular Dichroism in Organic Chemistry, 1, 93. 

In addition to chemical correlations discussed above, several physical methods are now available for the determination of the relative and absolute configurations of chiral sulfur compounds. Among these, NMR, infrared (IR), optical rotatory dispersion (ORD), circular dichroism (CD), and X-ray analysis are the most important. Sections III-B-1 to III-B-5 outline applications of these techniques for establishing the chirality around the sulfur atom. 

Optical Rotatory Dispersion, Recent Applications in Organic Chemistry (Crabbi) 1 93... 

The primary motivation for the development and application of vibrational optical activity lies in the enhanced stereochemical sensitivity that it provides in relation to its two parent spectroscopies, electronic optical activity and ordinary vibrational spectroscopy. Over the past 25 years, optical rotatory dispersion and more recently electronic circular dichroism have provided useful stereochemical information regarding the structure of chiral molecules and polymers in solution however, the detail provided by these spectra has been limited by the broad and diffuse nature of the spectral bands and the difficulty of accurately modeling the spectra theoretically. 

Salvwkm, P. and Ciaidelli, F. An Introduction to Chiroptical Technique Basic Principles, Definitions and Applications," In Optical Rotatory Dispersion and Circular Dichroism Ciaidelli, F. Savadori, P., Eds. Heyden London, 1973 pp. 3-24. 

The Octant Rule followed as a generalization of the axial haloketone rule and was presented, along with many examples, in C. Djerassi Optical Rotatory Dispersion and its Applications to Organic Chemistry, McGraw Hill, New York, 1960. 

The elucidation and confirmation of structure should include physical and chemical information derived from applicable analyses, such as (a) elemental analysis (b) functional group analysis using spectroscopic methods (i.e., mass spectrometry, nuclear magnetic resonance) (c) molecular weight determinations (d) degradation studies (e) complex formation determinations (f) chromatographic studies methods using HPLC, GC, TLC, GLC (h) infrared spectroscopy (j) ultraviolet spectroscopy (k) stereochemistry and (1) others, such as optical rotatory dispersion (ORD) or X-ray diffraction. 

More recently the relationship between absolute stereochemistry and spectroscopy has given rise to a good deal of work (11), and the increased availability of instruments for measuring either circular dichroism or optical rotatory dispersion (or both) has led to many applications in studies of molecular shape, including a good deal of work on metallo-enzymes. 

Tinoco, Ignacio, Jr., Application of Optical Rotatory Dispersion and Circular... 

---