Opium intoxicates

Naloxone may be of benefit in reversing the neurological and respiratory depressant effects of opium. A dose of 0.4-2.0 mg is given intravenously slowly, titrated to resumption of adequate respirations, and can be repeated as needed. The therapeutic effect of naloxone may be of shorter duration than that of opium activity therefore, it is imperative that opium intoxicated patients who demonstrated improvement after naloxone be closely monitored for resedation. Vital sign measurements and neurological checks should be monitored frequently until resolution. 

The fact that amalgame should be achieved nowhere more explicitly than in Un Mangeur d opium suggests another link, this time between the artificial paradises and alchemy. That the work of art can be associated with an intoxicating substance is suggested in Salon de 1859 where Delacroix s paintings are compared to wine ... 

The incitantia feVert thefe morbid motions more eertalnly, as opium and alcohol i and fellofc the natural heat more but if tliey induce any degree of intoxication, they are fucceeded by debility, when their ftimUlus ceafes ... 

P. ipecacuanha, native to South and Central America, is a well-known species used in therapy since the early seventeenth century due to emetic and expectorant activity and later as a medicine for amebic dysentery [98], being widely used as ingredient in pharmaceutical industry. Traditional communities use this plant for intoxication treatment due to its emetic effect [99], as well as stimulant and antidote to opium [100]. 

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