One-compartment scale-down systems

In a one-compartment scale-down system (OCSDS), heterogeneous conditions are created by the oscillatory variation of the operational set up of the bioreactor. Agitation rate, air flow rate, pressure, or substrate addition can be varied to reproduce the frequencies and oscillation periods of parameters such as DOT or... 

For the experimental simulation of gradients, the scale-down systems can be classified as one- and two-compartment systems. They are described below. 

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